=LDR 03507nam 22003972 4500 =001 c903706a-b89d-4587-8ddb-c6abff814381 =006 m\\\\\o\\d\\\\\\\\ =007 cr\\n\\\\\\\\\ =008 240919t20242024\\\\\\\\ob\\\\000\0\eng\d =020 \\$z9786053359166$q(Paperback) =024 7\$a10.69860/nobel.9786053359166$2doi =040 \\$aUkCbTOM$beng$elocal =072 7$aMJND$2bicssc =072 7$aMED089000$2bisacsh =072 7$aMKJD$2thema =245 00$aAlzheimer's Disease From Molecular Mechanisms to Clinical Practices /$cedited by Dildar KONUKOĞLU. =264 \1$aUS :$bNobel Tip Kitabevleri,$c2024. =264 \4$c©2024 =300 \\$a1 online resource (xvi + 346 pages): $b11 illustrations, 12 tables, 13 audio tracks, 14 videos. =336 \\$atext$btxt$2rdacontent =337 \\$acomputer$bc$2rdamedia =338 \\$aonline resource$bcr$2rdacarrier =500 \\$aAvailable through Nobel Tip Kitabevleri. =506 0\$aOpen Access$fUnrestricted online access$2star =520 \\$a“Alzheimer’s Disease: From Molecular Mechanisms to Clinical Practices” explores the extensive perspective from the molecular foundations to the clinical diagnosis and treatment of Alzheimer’s disease. The book serves as a fundamental resource for understanding the neurobiological basis and molecular pathogenesis of Alzheimer’s, while also discussing the challenges and opportunities of transitioning from the laboratory to clinical settings. The initial sections of the book comprehensively examine the fundamental molecular characteristics of Alzheimer’s disease; these include the accumulation of amyloid-beta peptide, hyperphosphorylation of tau protein, and how these processes lead to synaptic dysfunction and neuronal death. These chapters provide strategies on how to understand the pathology of the disease at a molecular level and how this knowledge can be translated into clinical practice. Subsequent parts focus on the development and use of biomarkers for the early diagnosis of Alzheimer’s disease. In addition to the role of genetic predispositions, the effects of environmental factors and lifestyle choices on Alzheimer’s disease are discussed, highlighting the multifactorial nature of the disease. In conclusion, this book is a valuable resource for clinicians, researchers, and medical students specializing in the field. It provides essential scientific and practical information necessary for a better understanding and management of Alzheimer’s disease, offering a comprehensive perspective on the integration of molecular mechanisms with clinical applications. =538 \\$aMode of access: World Wide Web. =540 \\$aThe text of this book is licensed under a custom license. For more detailed information consult the publisher's website.$uhttps://nobelpub.com/publish-with-us/copyright-and-licensing =588 0\$aMetadata licensed under CC0 Public Domain Dedication. =653 \\$aNeurology =653 \\$aGenetic =653 \\$aAlzheimer’s Disease =700 1\$aKONUKOĞLU, Dildar,$eeditor.$uIstanbul Cerrahpasa University.$0(orcid)000000026095264X$1https://orcid.org/0000-0002-6095-264X =710 2\$aNobel Tip Kitabevleri,$epublisher. =856 40$uhttps://doi.org/10.69860/nobel.9786053359166$zConnect to e-book =856 42$uhttps://nobelpub.com/wp-content/uploads/2024/06/Alzheimers-Disease-From-Molecular-Mechanisms-to-Clinical-Practices-scaled.jpg$zConnect to cover image =856 42$uhttps://creativecommons.org/publicdomain/zero/1.0/$zCC0 Metadata License